Relation Between Lipid Peroxidation and Body Mass Index(BMI), Percentage Body Fat (PBF) and Visceral Fat Area (VFA)

Abstract

Reactive oxygen derivatives and oxidative stress mediated by these compounds play important role in cancer, some neurological diseases, cardiovascular pathologies like atherosclerosis and some inflammatory diseases, obesity and aging. Obesity is known to be a very common condition. It has been shown that obesity is not only related with genetics and excessive food consumption, but also related with the increase in fat area and fat mass together with an increase in body mass index because of the insertion of reactive oxygen derivatives into lipid structures in the body. For that purpose, malondialdehyde (MDA) analysis has been used in scientific researches to determine the oxidative stress triggered by reactive oxygen derivatives which reveal lipid peroxidation products by being inserted in lipid structures. In this study, we have investigated the relationship between serum MDA levels and some important parameters of body composition analyzer in participants. Results of our study revealed a correlation between serum MDA levels and lean body mass (LBM), body mass index (BMI), percent body fat (PBF), visceral fat mass (VFM) and visceral fat area (VFA); however this correlation was statistically significant in females but not in men. In conclusion, results of our study show that, there is a correlation between the above parameters and oxidative stress which increase in obesity and trigger some pathological conditions, and this correlation is more significant in females compared to men.