Brucellozis and Deep Vein Thrombosis Coinfection: A Case Report and Review of the Literateur

Abstract

Brucellosis is a multisystem disease that can involve all tissues and organs. Vascular involvement of Brucellosis is rarely seen. In the present study, case of acute brucellosis associated with deep vein thrombosis (DVT) is presented. In June 2011, a 55-year-old male who had history of fever, body aches, and increasing pain in the right leg by walking for a duration of one week was admitted to the hospital. Dealing with livestock and consuming fresh cheese and milk were present in the history of the patient. His right leg was swollen compared to the left. On Doppler ultrasonographic examination of the lower right extremity, the right popliteal vein and vein Parva were observed to be thrombosed. Laboratory examination revealed white blood cells 7200/µL, platelet count 71.000 /µL, erythrocyte sedimentation rate 24 mm/h and C-reactive protein 3.91 mg/L; respectively. The other routine biochemical tests were normal. Standard Tube Agglutination test was 1/320 and Brucellacapt was 1/640. The patient was started on rifampicin and doxycyclin and was consulted to Cardiovascular Surgery. Anticoagulants and Brucella treatment were continued for three months. After one-year followup, the patient was asymptomatic, and no recurrence was observed. Patients with Brucellosis should be questioned in terms of DVT and in patients with DVT, Brucellosis should not be forgotten as an etiologic agent.